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| Antigenic Specificity | Cdk9, C-terminus |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat and mouse |
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| Isotype | n/a |
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| Format | delipidated & defibrinated |
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| Size | 100 µL |
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| Concentration | 75 mg/mL |
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| Applications | ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot. This antibody has been tested for use in ELISA, immunoprecipitation, immunohistochemistry and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 43 kDa corresponding to CDK9 (PITALRE) by western blotting in the appropriate cell lysate or extract. HeLa cells may be used as a positive control. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This product was prepared from monospecific antiserum by delipidation and defibrination. Antiserum will specifically react with a 43 kDa cdk9 (PITALRE) protein from human, rat and mouse tissue. No reaction was observed against other related cyclin dependent kinases. Cross reactivity with cdk9 (PITALRE) from other species may also occur. The murine cDNA is shown to be 98% identical with human. For immunohistochemistry use paraffin embedded tissue. |
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| Immunogen | Multiple synthetic peptides corresponding to C-terminal and N-terminal domains of the protein coded by the human gene cdk9 (PITALRE). |
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| Other Names | rabbit anti-Cdk9 Antibody, Cell division cycle 2 like protein kinase 4 antibody, Cell division protein kinase 9 antibody, rabbit anti-Cyclin dependent kinase 9 antibody, PITALRE antibody, Serine threonine protein kinase PITALRE antibody, TAK antibody, cdk |
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| Gene, Accession # | CDK9, Gene ID: 1025, NCBI: 4502747, UniProt: P50750 |
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| Catalog # | 100-401-167 |
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| Price | |
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| Order / More Info | Cdk9, C-terminus Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | Grana, X., DeLuca, A., Sang, N., Fu, Y., Claudio, P., Rosenblatt, J., Morgan, D. and Giordano, A. (1994) PITALRE a nuclear cdc2-related protein kinase that phosphorylates the retinoblastoma protein in vitro. Proc. Natl. Acd Sci. USA 91; 3834-3838.Bullrich, F., MacLachlan, T., Sang, N., Druck, T., Veronese, M.L., Allen, S., Chirazzi, N., Koff, A., Heubner, K., Croce, C. and Giordano, A. (1995) Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, PITALRE and a cdk inhibitor, p27, to regions involved in human cancer. Cancer Res. 55; 1199-1205. Bagella, L., MacLachlan, T.K., Buono, R.J., Pisano, M.M., Giordano, A. and De Luca, A. (1998) Cloning of murine cdk9/PITALRE and its tissue-specific expression in development. J. Cell Physiol. 177(2):206-13.MacLachlan, T.K., Sang, N., De Luca, A.., Puri, P.L., Levrero, M. and Giordano, A. and (1998) Binding of cdk9 to TRAF2. J. Cell Biochem. 71(4):467-478.De Falco, G. and Giordano, A. (1998) CDK( (PITALRE): A Multifunctional cdc-2-related Kinase. J. Cell. Physiol. 177; 501-506.Fujinaga, K., Cujec, T.P., Peng, J., Garriga, J., Price, D.H., Grana, X. and Peterlin, B.M. (1998) The ability of positive transcription elongation factor B to transactivate human immunodeficiency virus transcription depends on a functional kinase domain, cyclin T1 and Tat. J. Virol. 72(9) 7154-7159. |
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