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| Product Name | Flap Structure-Specific Endonuclease 1 (FEN1) (AA 1-380) protein |
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| Description | Flap Endonuclease 1 (FEN1) is a member of the XPG/RAD2 endonuclease family. During DNA replication, FEN1 cleaves the 5'-overhanging flap structure and processes the 5' ends of Okazaki fragments for synthesis. FEN1 also exhibits RNase H activity by possessing 5'-3' exonuclease activity on gapped double-stranded or nicked DNA, FEN1 is involved in the long patch base excision repair (LP-BER) pathway, it can cleave within the apurinic/apyrimidinic (AP) site-terminated flap. FEN1 can prevent flaps from equilibrating into structures that lead to duplications and deletions. FEN1 is also involved in replication and repair of rDNA and in repairing mitochondrial DNA.Alternative Names: Flap Endonuclease 1, FEN-1, DNase IV, Flap Structure-Specific Endonuclease 1, Maturation Factor 1, MF1, hFEN-1, FEN1, RAD2 |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FEN-1|FEN1|AW538437|MF1|RAD2|cb879|fen-1|fen1|mf1|rad2|xFEN1a |
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| Gene, Accession, CAS # | Gene ID: 2237 |
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| Catalog # | ABIN1096674 |
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| Order / More Info | Flap Structure-Specific Endonuclease 1 (FEN1) (AA 1-380) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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