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Product Name | Flap Structure-Specific Endonuclease 1 (FEN1) (AA 1-380) protein |
Description | FEN-1, also known as Flap structure-specific endonuclease 1, removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. FEN-1 is highly homologous to yeast Rad2. The C-terminal region of FEN-1 may bind to PCNA, thus allowing FEN-1 to function as an exonuclease in DNA replication. Recombinant human FEN-1 protein was expressed in E. coli and purified by using conventional chromatography techniques. Alternative Names: Flap structure specific endonuclease 1 protein, Flap endonuclease 1 protein, Maturation factor 1 protein, MF1 protein, hFEN1 protein, RAD2 protein, FEN 1, FEN-1, Flap structure-specific endonuclease 1 DNase IV protein, FEN 1 protein, FEN-1 protein, FEN-1 protein, , FEN1 |
Size | 100 µg |
Concentration | n/a |
Applications | SDS-PAGE (SDS) |
Other Names | FEN-1|FEN1|AW538437|MF1|RAD2|cb879|fen-1|fen1|mf1|rad2|xFEN1a |
Gene, Accession, CAS # | Gene ID: 2237 |
Catalog # | ABIN935077 |
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Order / More Info | Flap Structure-Specific Endonuclease 1 (FEN1) (AA 1-380) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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