| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | H5N1 |
|---|
| Clone | 8A3 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | n/a |
|---|
| Isotype | IgG2b kappa |
|---|
| Format | Protein A purified |
|---|
| Size | 100 µg |
|---|
| Concentration | 1.0 mg/mL |
|---|
| Applications | ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot. Hemagglutinin of A/Vietnam/1203/04 Influenza Virus (VN04-10) monoclonal antibody can be used for hemagglutination inhibition (HI) assays to provide antigenic characterization of the influenza A viruses of the H5 HA subtype. This monoclonal antibody is suitable for virus neutralization assays (in cell culture and in embryonated chicken eggs), ELISA, immunoprecipitation, immunohistochemistry and western blotting. |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | H5N1 Antibody was purified from tissue culture supernatant fluid by Protein A chromatography and is specific for H5 hemagglutinin (HA) protein of influenza A virus [strain A/Vietnam/1203/04 (H5N1)]. VN04-10 monoclonal antibody did not cross-react with influenza viruses of other HA subtypes. This monoclonal antibody reacted with H5N1 influenza viruses representatives of different clades and subclades of the H5 HA subtype. |
|---|
| Immunogen | Hemagglutinin of A/Vietnam/1203/04 Influenza Virus (VN04-10) monoclonal antibody was produced by intraperitoneal immunization of BALB/c mice with concentrated purified virus preparation containing hemagglutinin (HA) protein of influenza A virus [strain A/Vietnam/1203/04 (H5N1)] using the modification of the method described by Kohler and Milstein. Each mouse received two immunizations of 15 µg HA with incomplete Freund's adjuvant, administered 3 week apart. |
|---|
| Other Names | mouse anti-H5N1 Antibody, mouse anti-VN04-10 Antibody, H5HA antibody, Hemagglutinin 5 antibody, H5N1 antibody |
|---|
| Gene, Accession # | HA, NCBI: 159144921, UniProt: A8UDQ2 |
|---|
| Catalog # | 200-301-978 |
|---|
| Price | |
|---|
| Order / More Info | H5N1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
|---|
| Product Specific References | Govorkova, E.A., et al. (2006) Immunization with Reverse-Genetics-Produced H5N1 Influenza Vaccine Protects Ferrets against Homologous and Heterologous Challenge. J. Infect. Dis. 194:159-167.Hoffmann, E., et al. (2005) Role of Specific Hemagglutinin Amino Acids in the Immunogenicity and Protection of H5N1 Influenza Virus Vaccines. Proc. Natl. Acad. Sci. 102(36): 12915-12920.ML Reed, HL Yen, RM DuBois, OA Bridges, R Salomon, RG Webster, CJ Russell. (2009). Amino Acid Residues in the Fusion Peptide Pocket Regulate the pH of Activation of the H5N1 Influenza Virus Hemagglutinin Protein. J Virol. 2009 April; 83(8): 3568:3580. BJ Hanson, A Boon, APC Lim, A Webb, EE Ooi, RJ Webby. (2006). Passive immunoprophylaxis and therapy with humanized monoclonal antibody specific for influenza A H5 hemagglutinin in mice. Respiratory Research 2006, 7:126. |
|---|
| 产品资料 |
|
|