| 产品详情 |
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| Antigenic Specificity | Human IgG4 |
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| Clone | polyclonal |
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| Host Species | Sheep |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 0.5 mg |
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| Concentration | 1.0mg/mL |
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| Applications | ELISA, Immunohistochemistry, Western Blot. Anti-Human IgG4 Antibody has been tested in IEP, WB, ELISA, double diffusion, and IHC. May be useful in multiple assays. Specific conditions for reactivity should be optimized by the end user. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This polyclonal antibody is directed against human IgG4 and is affinity purified. Cross reactivity with other animal sera has not been tested. Anti-Human IgG4 generated in sheep detects human Immunoglobulin IgG4. Human IgG is composed of four peptide chains - two heavy chains gamma and two light chains held together by disulfide bonds. The resulting Y structure has two identical halves which at the end of each end contains an identical antigen binding site. The Fc regions of IgGs bear a highly conserved N-glycosylation site. IgG affinity to the Fc receptors is specific to the host as well as class. Humans have 4 subclasses (IgG1, 2, 3, 4) present in serum, with IgG1 being most abundant and has the highest affinity to the Fc receptor. IgG4 is the least abundant subclass with the intermediate affinity for Fc binding. Secondary Antibodies are available in a variety of formats and conjugate types. When choosing a secondary antibody product, consideration must be given to species and immunoglobulin specificity, conjugate type, fragment and chain specificity, level of cross-reactivity, and host-species source and fragment composition. |
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| Immunogen | Anti-Human IgG4 was produced in sheep by repeated immunizations with human IgG4 (Kappa and lambda) protein purified from human myeloma sera shown to be pure by SDS-PAGE and IEP. |
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| Other Names | Sheep Anti-Human IgG4 Antibody, Sh Anti-Hu IgG4 |
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| Gene, Accession # | n/a |
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| Catalog # | 600-601-ME0 |
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| Price | |
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| Order / More Info | Human IgG4 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | n/a |
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