| 产品详情 |
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| Antigenic Specificity | Cul4A, N-terminus |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | delipidated & defibrinated |
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| Size | 100 µL |
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| Concentration | 85 mg/mL |
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| Applications | ELISA, Immunohistochemistry, Western Blot. This antibody reacts with human Cul4A by western blot and immunoprecipitation. The antibody immunoprecipitates protein from cell lysates (using HeLa, U2OS and others). This antibody also co-immunoprecipitates at least 8 subunits of COP9, DDB1 and CAND1. An 87.6 kDa band corresponding to human Cul4A is detected. Most cell lines expressing Cul4A can be used as a positive control. Researchers should determine optimal titers for other applications. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human Cullin 4A. Cross reactivity is expected against mouse Cul4A based on a high degree of sequence homology. Cross reactivity with other human cullins may occur. |
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| Immunogen | This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 1-20 of Human Cul4A (N-terminus) coupled to KLH. |
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| Other Names | rabbit anti-Cul4A Antibody, 2810470J21Rik antibody, AW495282 antibody, CUL 4A antibody, CUL4A antibody, Cul4a protein antibody, MGC36573 antibody, MGC64071 antibody, CUL, Cullin |
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| Gene, Accession # | CUL4A, Gene ID: 8451, NCBI: 38176422, UniProt: Q13619 |
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| Catalog # | 100-401-A04 |
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| Price | |
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| Order / More Info | Cul4A, N-terminus Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | Higa,L.A., Mihaylov,I.S., Banks,D.P., Zheng,J. and Zhang,H. (2003) Radiation-mediated proteolysis of CDT1 by CUL4-ROC1 and CSN complexes constitutes a new checkpoint. Nat. Cell Biol. 5 (11), 1008-1015.Kipreos,E.T., Lander,L.E., Wing,J.P., He,W.W. and Hedgecock,E.M. (1996) cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. Cell 85 (6), 829-839.Michel,J.J. and Xiong,Y. (1998) Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A. Cell Growth Differ. 9 (6), 435-449. |
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