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Antigenic Specificity | Cul7, C-terminus |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | delipidated & defibrinated |
Size | 100 µL |
Concentration | 85 mg/mL |
Applications | ELISA, Immunohistochemistry, Western Blot. This antibody reacts with human and mouse Cul7 by western blot and immunoprecipitation. The antibody immunoprecipitates in vitro translated protein and also immunoprecipitates protein from cell lysates (using HeLa, NIH-3T3, and others). This antibody also co-immunoprecipitates associated proteins in overexpressed CUL7 systems. A 191.2 kDa band corresponding to human Cul7 is detected. Most cell lines expressing Cul7 can be used as a positive control. Researchers should determine optimal titers for other applications. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human and mouse Cullin 7. Cross reactivity with other human cullins may occur. |
Immunogen | This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 1679-1698 of Human Cul7 (C-terminus) coupled to KLH. |
Other Names | rabbit anti-Cul7 Antibody, rabbit anti-Cullin7 antibody, CUL, Cullin |
Gene, Accession # | CUL7, Gene ID: 9820, NCBI: 41872646, UniProt: Q14999 |
Catalog # | 100-401-A06 |
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Order / More Info | Cul7, C-terminus Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | Arai,T., Kasper,J.S., Skaar,J.R., Ali,S.H., Takahashi,C. and DeCaprio,J.A. (2003) Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis. Proc. Natl. Acad. Sci. U.S.A. 100 (17), 9855-9860.Dias,D.C., Dolios,G., Wang,R. and Pan,Z.Q. (2002) CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex. Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16601-16606. |
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