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| Product Name | Human Neuroserpin protein |
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| Description | Neuroserpin is an inhibitory serpin that is expressed predominantly in central nervous system. Although the physiological targetof neuroserpin is still unclear, cumulative evidence suggest that it plays an important role in controlling proteolytic degradationof extracellular matrix (ECM) during synaptogenesis and the subsequent development of neuronal plasticity. The neuroprotectiverole of neuroserpin has been demonstrated in transgenic mice lacking neuroserpin expression. The deficiency of neuroserpin inthese mice was associated with motor neuron disease characterized by axonal degradation. In humans, defects in neuroserpin,caused by point mutations in the neuroserpin gene, underlie a hereditary disorder called the familial encephalopathy withneuroserpin inclusion bodies (FENIB). MW: 44.8kDa. Purity > 95% by SDS-PAGE and HPLC analyses |
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| Size | 5 ug, 25 ug, 1 mg, 100 ug, 250 ug, 500 ug |
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| Concentration | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
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| Applications | HPLC, SDS-PAGE |
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| Other Names | Human Neuroserpin protein |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | orb107789 |
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| Order / More Info | Human Neuroserpin protein from BIORBYT LTD. |
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| Product Specific References | n/a |
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