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| Product Name | 2-Hydroxyestradiol |
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| Description | Purity >95%. 2-hydroxy Estradiol (2-HE2) is a cytochrome P450 metabolite of estradiol with low affinity for estrogen receptors. 2-HE is rapidly metabolized by catechol-O-methyltransferase (COMT) to form 2-methoxy estradiol (2-ME2) with a half-life of approximately ten minutes in rat. 2-ME2 has achieved considerable attention as an anti-cancer agent acting as an angiogenesis inhibitor via the HIF-1a pathway. Due to the rapid metabolism of 2-HE2, the effects attributed to 2-HE2, may actually be those of 2-ME2. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | estra-1,3,5(10)-triene-2,3,17Beta-triol, 2-HE2, NSC 61711 |
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| Gene, Accession, CAS # | CAS: 362-05-0 |
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| Catalog # | LS-H5996 |
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| Order / More Info | 2-Hydroxyestradiol from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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