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| Product Name | Recombinant Human General transcription factor IIH subunit 5 |
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| Description | 1-71aa; Full Length. MW: 35.4kD. Purity >90% as determined by SDS-PAGE. Component of the TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Necessary for the stability of the TFIIH complex and for the presence of normal levels of TFIIH in the cell. |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [General transcription factor IIH polypeptide 5TFB5 ortholog; TFIIH basal transcription factor complex TTD-A subunit] |
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| Gene, Accession, CAS # | GTF2H5, Gene ID: 404672, Accession: NP_997001.1 |
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| Catalog # | MBS1265178 |
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| Order / More Info | Recombinant Human General transcription factor IIH subunit 5 from MYBIOSOURCE INC. |
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| Product Specific References | A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A and stabilizes TFIIH.Giglia-Mari G., Coin F., Ranish J.A., Hoogstraten D., Theil A., Wijgers N., Jaspers N.G.J., Raams A., Argentini M., van der Spek P.J., Botta E., Stefanini M., Egly J.-M., Aebersold R., Hoeijmakers J.H.J., Vermeulen W.Nat. Genet. 36:714-719(2004) The DNA sequence and analysis of human chromosome 6.Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jo |
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