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Product Name | Recombinant Rat Gremlin-1 (Grem1) |
Description | 25-184aa; Full Length. MW: 20,680 Da. Purity ≥90%. Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed. |
Size | 0.01 mg (E-Coli), 0.01 mg (Baculovirus), 0.01 mg (Mammalian-Cell), 0.05 mg (E-Coli), 0.1 mg (E-Coli) |
Concentration | n/a |
Applications | n/a |
Other Names | [Gremlin-1; Cysteine knot superfamily 1, BMP antagonist 1; Down-regulated in Mos-transformed cells protein] |
Gene, Accession, CAS # | Grem1, Gene ID: 50566, Accession: NP_062155.1 |
Catalog # | MBS1243813 |
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Order / More Info | Recombinant Rat Gremlin-1 (Grem1) from MYBIOSOURCE INC. |
Product Specific References | n/a |
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