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Product Name | Human CD32a Recombinant (FcgRIIa) |
Description | MW: 35,001 Da. Purity >95%, as determined by SDS-PAGE and HPLC. FcγRIIA is expressed on cells ofboth myeloid and lymphoid lineages as well as on cells of non- hematopoietic origin.Associated with an ITAM (immunoreceptor tyrosine-based activation motif) -bearing adapter subunit,FcRγ,CD32a (FcγRIIA) d elivers an activating signal upon ligand binding,and results in the initiation of inflammatory responses including cytolysis,phagocytosis,degra nulation and cytokine production.The res |
Size | 0.02 mg, 0.1 mg, 0.5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | [Human CD32a Recombinant (Fcg RIIa) ; Human CD32a Recombinant (Fcgamma RIIa) ; cd32; cd-32] |
Gene, Accession, CAS # | CD32, Gene ID: 2212, Accession: NP_001129691.1 |
Catalog # | MBS553040 |
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Order / More Info | Human CD32a Recombinant (FcgRIIa) from MYBIOSOURCE INC. |
Product Specific References | • dynamics of the interaction of human igg subtype immune complexes with cells expressing r and h allelic forms of a low-affinity fc receptor CD32a .J. Immunol., Dec 2009; 183: 8216 - 8224. • association of fcriia (CD32a) with lipid rafts regulates ligand binding activity .J. Immunol., Jun 2009; 182: 8026 - 8036. • transgenic expression of human platelet fcriia (CD32a) in mice does not affect the thrombocytopenia associated with wasp deficiency. .Blood (ASH Annual Meeting Abstract |
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