| 产品详情 |
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| Product Name | P7C3 |
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| Description | Purity >98% by NMR, TLC. P7C3 exerts proneurogenic activity by protecting newborn neurons from apoptosis. Prolonged administration to aged rats impedes neuronal death and preserves cognitive capacity. Delays disease progression in G93A-SOD2 mutant mouse model of amyotrophic lateral sclerosis. Blocks MPTP-mediated cell death of dopaminergic neurons in the substantia nigra of adult mice, a model of Parkinson disease. Restores hippocampal neurogenesis in a mouse model of Down Syndrome. The mechanism of action involves activation of nicotinamide phosphoribosyltransferase (NAMPT) with concomitant increase of intracellular levels of NAD. Active in vivo. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-(3,6-Dibromo-9H-carbazol-9-yl)-3-(phenylamino)propan-2-ol |
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| Gene, Accession, CAS # | CAS: 301353-96-8 |
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| Catalog # | LS-H14796 |
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| Order / More Info | P7C3 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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