产品名称 Pyronaridine (phosphate) from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H9610
产品价格 现货询价,电话:010-67529703
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产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NamePyronaridine (phosphate)
DescriptionPurity >98%. Pyronaridine (PND) is a potent antimalarial compound developed in China over 40 years ago. It inhibits the growth of P. falciparum during the asexual stage and early gametocyte stages (I and II) with an IC50 value of approximately 10 nM. PND is highly effective against artemisinin-resistant malaria and can be used in combination therapy, particularly with the artemisinin derivative, artesunate . PND, alone or in combination with artesunate, prevents recrudescence of parasites. Resistance to pyronaridine may be linked to genetic variations in the P. falciparum multidrug resistance protein 1.
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Other Names4-[(7-chloro-2-methoxybenzo[b]-1,5-naphthyridin-10-yl)amino]-2,6-bis (1-pyrrolidinylmethyl)-phenol, tetraphosphate, PND
Gene, Accession, CAS #CAS: 76748-86-2
Catalog #LS-H9610
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Order / More InfoPyronaridine (phosphate) from LIFESPAN BIOSCIENCES INC.
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