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| Product Name | Human IL12 Protein (Recombinant) |
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| Description | Purity >95% by SDS-PAGE and HPLC, MW: 35 kDa. Interleukin 12 (IL-12), also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a pleiotropic cytokine originally identified in the medium of activated human B lymphoblastoid cell lines. The p40 subunit of IL-12 has been shown to have extensive amino acid sequence homology to the extracellular domain of the human IL-6 receptor while the p35 subunit shows distant but significant sequence similarity to IL-6, G-CSF, and chicken MGF. These observations have led to the suggestion that IL-12 might have evolved from a cytokine/soluble receptor complex. Human and mouse IL-12 share 70% and 60% amino acid sequence homology in their p40 and p35 subunits, respectively. IL-12 apparently shows species specificity with human IL-12 reportedly showing minimal activity in the mouse system. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL-12 |
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| Gene, Accession, CAS # | IL-12 |
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| Catalog # | LS-G27120 |
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| Order / More Info | Human IL12 Protein (Recombinant) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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