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Antigenic Specificity | V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) |
Clone | 7E10 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blotting (WB),ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.Synonyms: MRTL, c-Myc, bHLHe39 |
Immunogen | Purified recombinant fragment of human MYC expressed in E. Coli. |
Other Names | LOC100136746|RNCMYC|c-myc|mMyc|AU016757|Myc2|Niard|Nird|bHLHe39|MYC|cmyc|zc-myc|MRTL|MYCC|c-Myc|C-MYC|CMYC|CMyc |
Gene, Accession # | Gene ID: 4609 |
Catalog # | ABIN966613 |
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Order / More Info | V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 18951706, 19748357 |
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