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| Antigenic Specificity | V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) |
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| Clone | PMYCSHG |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | 0.5 mg |
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| Concentration | n/a |
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| Applications | Immunoprecipitation (IP),Transfected Cell Culture (TCC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this geneSynonyms: MYC, CMYC, C-MYS, V-MYC, P64 |
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| Immunogen | Monoclonal antibodies are produced by immunizing mouse with synthetic peptide (EQKLISEEDL) coupled to KLH |
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| Other Names | LOC100136746|RNCMYC|c-myc|mMyc|AU016757|Myc2|Niard|Nird|bHLHe39|MYC|cmyc|zc-myc|MRTL|MYCC|c-Myc|C-MYC|CMYC|CMyc |
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| Gene, Accession # | n/a |
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| Catalog # | ABIN808330 |
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| Order / More Info | V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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