| 产品详情 |
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| Antigenic Specificity | V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Members of the Myc/Max/Mad network function as transcriptional regulators with roles in various aspects of cell behavior including proliferation, differentiation and apoptosis . These proteins share a common basic-helix-loop-helix leucine zipper (bHLH-ZIP) motif required for dimerization and DNA-binding. Max was originally discovered based on its ability to associate with c-Myc and found to be required for the ability of Myc to bind DNA and activate transcription . Subsequently, Max has been viewed as a central component of the transcriptional network, forming homodimers as well as heterodimers with other members of the Myc and Mad families . The association between Max and either Myc or Mad can have opposing effects on transcriptional regulation and cell behavior . The Mad family consists of four related proteins, Mad1, Mad2 (Mxi1), Mad3 and Mad4, and the more distantly related members of the bHLH-ZIP family, Mnt and Mga. Like Myc, the Mad proteins are tightly regulated with short half-lives. In general, Mad family members interfere with Myc-mediated processes such as proliferation, transformation and prevention of apoptosis by inhibiting transcription . Synonyms: MYC, MRTL,bHLHe39 ,c-Myc,Myc proto-oncogene protein ,Proto-oncogene c-Myc ,Transcription factor p64 , |
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| Immunogen | Fusion protein of human c-Myc |
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| Other Names | LOC100136746|RNCMYC|c-myc|mMyc|AU016757|Myc2|Niard|Nird|bHLHe39|MYC|cmyc|zc-myc|MRTL|MYCC|c-Myc|C-MYC|CMYC|CMyc |
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| Gene, Accession # | Gene ID: 4609,24577 |
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| Catalog # | ABIN1684170 |
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| Order / More Info | V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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