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| Product Name | Recombinant Dog Tight junction protein ZO-1 |
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| Description | 1633-1769aa; Partial. MW: 18.77kD. Purity >90% as determined by SDS-PAGE. The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells. |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Tight junction protein 1; Zona occludens protein 1; Zonula occludens protein 1] |
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| Gene, Accession, CAS # | TJP1, Gene ID: 403752, Accession: NP_001003140.1 |
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| Catalog # | MBS1235259 |
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| Order / More Info | Recombinant Dog Tight junction protein ZO-1 from MYBIOSOURCE INC. |
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| Product Specific References | Molecular characterization of the tight junction protein ZO-1 in MDCK cells.Gonzalez-Mariscal L., Islas S., Contreras R.G., Garcia-Villegas M.R., Betanzos A., Vega J., Diaz-Quinonez A., Martin-Orozco N., Ortiz-Navarrete V., Cereijido M., Valdes J.Exp. Cell Res. 248:97-109(1999) The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB.Tsapara A., Matter K., Balda M.S.Mol. Biol. Cell 17:1322-1330(2006) |
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