| 产品详情 |
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| Product Name | 16(R)-AFP 07 (free acid) |
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| Description | Purity >97%. Prostaglandin I2 is an unstable prostanoid which, through the 'I prostanoid' (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds. AFP 07 is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor (Ki = 0.561 nM). AFP 07 shows weaker affinity for EP receptors, with Ki values > 100 nM for EP 1-3 and > 10 nM for EP4. 16(R)-AFP 07 is an epimer of AFP 07. Its biological properties, particularly through the IP and EP receptors, remain to be evaluated. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5Z-[3aR,3-difluorohexahydro-5R-hydroxy-4R-[3R-hydroxy-4S-methyl-1E-nonen-6aS-ynyl]-2Hcyclopenta[b]furan-2-ylidene]-pentanoic acid |
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| Gene, Accession, CAS # | CAS: 773825-80-2 |
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| Catalog # | LS-H73 |
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| Order / More Info | 16(R)-AFP 07 (free acid) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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