产品详情 |
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Antigenic Specificity | COL9A1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:10-1:50, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | COL9A1 Polyclonal Antibody. COL9A1 is one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule,and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in the COL9A1 gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. |
Immunogen | n/a |
Other Names | Collagen alpha-1(IX) chain [Precursor]; COL9A1 |
Gene, Accession # | Entrez: 1297; Uniprot: P20849 |
Catalog # | PA5-12348 |
Price | |
Order / More Info | COL9A1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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