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| Product Name | Cdk1/5 Inhibitor |
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| Description | Purity >95%. Cyclin-dependent kinases (Cdks) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Cdk1/5 Inhibitor is a pyrazolo [3,4-b] quioxaline that inhibits Cdk1/cyclin B and Cdk5/p25 (IC50 s = 600 and 400 nM, respectively). It less potently inhibits GSK3Beta (IC50 = 1 µM) and does not block Cdc25 activity. This compound is used to help define the roles of Cdk1 and Cdk5 in various signaling pathways. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1H-pyrazolo[3,4-b]quinoxalin-3-amine, Cyclin-dependent kinase 1/5 Inhibitor, NSC 693868 |
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| Gene, Accession, CAS # | CAS: 40254-90-8 |
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| Catalog # | LS-H7042 |
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| Order / More Info | Cdk1/5 Inhibitor from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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