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| Product Name | Angiopoietin-2, Recombinant, Human (Ang-2, Ang2, Angpt2) |
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| Description | Purity ≥95% (SDS-PAGE). Endotoxin: <0.01EU/ug (LAL test; Lonza). Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context. Sequence: Human angiopoietin-2 (aa19-496) is fused at the N-terminus to a FLAG®-tag, expressed in HEK 293 cells. Binds to the human and mouse Tie-2 receptor. Molecular Weight: ~70kD (SDS-PAGE) |
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| Size | 10ug, 3x10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: O15123 |
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| Catalog # | 44504 |
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| Order / More Info | Angiopoietin-2, Recombinant, Human (Ang-2, Ang2, Angpt2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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