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| Product Name | Angiostatin K 1-3, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE, HPLC). Ang K1-3 is a single, non-glycosylated polypeptide chain containing 259aa. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. A specific inhibitor of endothelial cell growth and angiogenesis. Displays increased inhibitory activity (ED50=70nM) relative to kringles 1-4 (ED50=135nM). Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth. Source: Recombinant protein corresponding to human Angiostatin K1-3 expressed in E. coli. Molecular Weight: ~30kD (259aa) Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Biological Activity: The activity is assayed on anti-proliferation and anti-migration of endothelial cells in vitro and anti-angiogenesis in vivo. The specific activity of anti-migration of endothelial cells in vitro is 0.55x10e5Units/mg. Endotoxin: <1EU/ug (LAL) AA |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 359785 |
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| Order / More Info | Angiostatin K 1-3, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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