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| Product Name | Angiotensin Converting Enzyme, Recombinant, Mouse, inactive (ACE, ACE1, DCP1) (Control Peptide) |
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| Description | Highly purified. Western Blot Control Peptide for A2295-01L (affinity purified antibody). Renin-Angiotensin System (RAS) is a crtical regulator of blood pressure homeostasis. The protease renin cleaves angiotensinogen into inactive decameric peptide angiotensin-I (Ang-I). Angiotensin-converting enzyme (ACE) then cleaves C-terminal dipeptide from Ang-I to form an active octamer angiotensin-II (Ang-II), which can contribute to hypertension by promoting vascular smooth muscle vasocontriction and renal tubule sodium reabsorption. ACE can also cleave many other small peptides including the vasodialating peptide bradykinin into inactive fragment, cleave Alzheimer amyloid beta-peptide (Abeta), retard Abeta aggregation, deposition and fibril formation. ACE mutant mice display spontaneous hypotension, partial male infertility and kidney malformations. ACE is found in somatic (s-ACE) and testicular/germinal (t-ACE) isoforms. The products of renin and ACE catalysis, namely Ang1-10 and Ang1-8 can |
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| Size | 100ul |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | A2295-01K1 |
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| Order / More Info | Angiotensin Converting Enzyme, Recombinant, Mouse, inactive (ACE, ACE1, DCP1) (Control Peptide) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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