| 产品详情 |
| Edit |   |
|---|
| Product Name | KLF5 Inhibitor, CID 5951923 |
|---|
| Description | Purity ~99% (HPLC). A cell-permeable phenylpropenoate compound that inhibits the proliferation of colon cancer cell lines exhibiting high levels of KLF5 (IC50=1.6uM in DLD-1 cells). Downregulates the expression of early growth response protein 1 (EGR1), which modulates KLF5 expression at transcription level. Shown to activate the EGFR/ERK pathway by stimulating phosphorylation of EGFR-Tyr1068 and ERK1/2-Thr202/Tyr204. Also, up-regulates the phosphorylation of p38 MAPK-Thr180/Tyr182. Formula: C16H18N2O7S Molecular Weight: 382.4 Solubility: DMSO (50mg/ml) |
|---|
| Size | 10mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | KLF5 Inhibitor, CID 5951923 (2-((1,1-Dioxidotetrahydrothiophen-3-yl, methyl)amino)-2-oxoethyl-(2E)-3-(3-nitrophenyl)prop-2-enoate) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 217493 |
|---|
| Price | |
|---|
| Order / More Info | KLF5 Inhibitor, CID 5951923 from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|