| 产品详情 |
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| Antigenic Specificity | CBF-beta (isoform 1) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-10 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CBF-beta (isoform 1) Polyclonal Antibody. CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. |
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| Immunogen | n/a |
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| Other Names | CBF-beta, PEA2-beta, PEBP2B, PEBP2-beta, polyomavirus enhancer binding protein 2, beta subunit, polyomavirus enhancer-binding protein 2 beta subunit, SL3/AKV core-binding factor beta subunit, SL3-3 enhancer factor 1 beta subunit, SL3-3 enhancer factor 1 subunit beta |
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| Gene, Accession # | Entrez: 12400, 865; Uniprot: Q08024, Q13951 |
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| Catalog # | A303-549A |
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| Price | |
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| Order / More Info | CBF-beta (isoform 1) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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