| 产品名称 |
ICOS, Recombinant, Human, aa21-140, hIgG-His-Tag (Inducible T-Cell Costimulator, ICOS, AILIM, CD278, CVID1) from UNITED STATES BIOLOGICAL |
| 产品详情 |
| Edit |   |
|---|
| Product Name | ICOS, Recombinant, Human, aa21-140, hIgG-His-Tag (Inducible T-Cell Costimulator, ICOS, AILIM, CD278, CVID1) |
|---|
| Description | Purity ~90% (SDS-PAGE). ICOS, also known as inducible T-cell costimulator, is a member of the CD28 family of immune- assisted stimulatory receptors. The interaction of B7-H2 / ICOS plays a crucial role in Th cell differentiation, T-B cell interaction and humoral immune response essential for the formation of reproductive centers and the production of cytokine IL-4. In addition, this protein is more potent in inducing IL-10 production, a cytokine important for the inhibitory function of T regulatory cells. The B7-1 / B7-2-CD28 / CTLA-4 and ICOS-B7RP-1 pathways provide an important second signal that can regulate the activation, inhibition and fine regulation of T-lymphocyte responses. It stimulates production of Th1 and Th2 cytokines, but may play a role in the generation of Th2 cells. Recombinant human ICOS, fused to hIgG-His-Tag at C-terminal, expressed in insect cell and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa21-140 of human ICOS, fused to hI |
|---|
| Size | 20ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | Accession: NP_036224 |
|---|
| Catalog # | 396881 |
|---|
| Price | |
|---|
| Order / More Info | ICOS, Recombinant, Human, aa21-140, hIgG-His-Tag (Inducible T-Cell Costimulator, ICOS, AILIM, CD278, CVID1) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|