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| Product Name | Interleukin 18 Binding Protein (IL18BP), BioAssay™ ELISA Kit (Human) |
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| Description | Interleukin-18-binding protein, also known as IL18BPa, is a protein that in humans is encoded by the IL18BP gene. It is mapped to 11q13.4. The protein encoded by this gene is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. It has been found that IL18BP expression in intestinal tissue is increased in endothelial cells as well as cells of the submucosa and overlying lymphoid aggregates in Crohn disease. Sample Type: Cell culture supernates, serum, plasma (heparin, EDTA) and urine Intended Use: For quantitative detection of human IL-18BP in cell culture supernates, serum, plasma (heparin, EDTA) and urine. Sensitivity: <10pg/ml Range: 93.7-6000pg/ml Specificity: Natural and recombinant human IL-18BP Test Principle: This human I |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 10068, SwissProt: O95998 |
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| Catalog # | 352946 |
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| Order / More Info | Interleukin 18 Binding Protein (IL18BP), BioAssay™ ELISA Kit (Human) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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