| 产品详情 |
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| Product Name | Cyclophilin D |
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| Description | Highly Purified. C-DENFHYKHDREG, from the internal region of human PPID. Control peptide corresponding to polyclonal antibody, Catalog#C8855-20B, goat x human. Cyclophilin D (CyPD) is a member of the immunophilin family of proteins. Immunophilins are a family of soluble cytosolic receptors capable of binding to one of two major immunosuppressant agents-cyclosporin A (CsA) or FK506. Proteins which bind FK506 are termed FK506 Binding Proteins (FKBP's) and those which bind cyclosporin A are called cyclophilins (CyP). Immunophilins function as peptidyl prolyl cis-trans-isomerases (PPIase) whose activity is inhibited by their respective immunosuppressant compounds. As PPIase's, immunophilins accelerate folding of some proteins both in vivo and in vitro by catalyzing slow steps in the initial folding and rearrangement of proline containing proteins. CyPD is located in the inter-membrane space of the mitochondria where it has been shown to be an integral member of the permeability transition |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | Cyclophilin D (PPID, Peptidylprolyl Isomerase D, 40kD Peptidyl-Prolyl cis-trans isomeras, Cyclophilin-40, Cyclophilin-Related Protein, CYP40, CYP-40, CYPD, MGC33096, PPIase, Rotamase) (Control Peptide) |
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| Gene, Accession, CAS # | Accession: NP_005029.1 |
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| Catalog # | C8855-20B-P |
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| Order / More Info | Cyclophilin D from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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