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| Product Name | Recombinant Human DNA repair protein XRCC4 (XRCC4) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 65.3kDa. Full Length: 1-336aa. N-terminal GST-tagged. Homo sapiens (Human). Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V (D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | X-ray repair cross-complementing protein 4 |
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| Gene, Accession, CAS # | XRCC4, UniProt: Q13426 |
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| Catalog # | RPC22979 |
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| Order / More Info | Recombinant Human DNA repair protein XRCC4 (XRCC4) from BIOMATIK |
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| Product Specific References | n/a |
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