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| Product Name | Recombinant Human DNA replication licensing factor MCM2 (MCM2) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 105.8kDa. Full Length of Mature Protein: 2-904aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Minichromosome maintenance protein 2 homologNuclear protein BM28 |
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| Gene, Accession, CAS # | MCM2, UniProt: P49736 |
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| Catalog # | RPC21656 |
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| Order / More Info | Recombinant Human DNA replication licensing factor MCM2 (MCM2) from BIOMATIK |
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| Product Specific References | n/a |
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