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| Product Name | SIK3, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). SIK3 (QSK) is a serine/threonine-protein kinase, belongs to QIK subfamily. The phosphorylation of SIK3 by LKB1 through the 14-3-3 binding enhances its catalytic activity and leads its localization to punctate structures within the cytoplasm. Overexpression of SIK3 promotes G1/S cell cycle progression with ovarian cancer. There are two sites (H331L and A1103V) were mutated at significant frequency in breast cancer. SIK3 is a novel tumor-associated antigen (TAA). Source: Recombinant protein corresponding to human SIK3, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~62kD Specific Activity: 140nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SIK3, Recombinant, Human, GST-Tag (Serine/threonine-protein kinase SIK3, Salt-inducible kinase 3, Serine/threonine-protein kinase QSK, QSK, SIK-3, L19, FLJ12240, KIAA0999) |
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| Gene, Accession, CAS # | Accession: BC128510, SwissProt: Q9Y2K2 |
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| Catalog # | 500450 |
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| Order / More Info | SIK3, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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