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| Product Name | sIL-2Rα, Recombinant, Human (soluble IL-2 receptor, TAC-antigen, CD25 antigen) |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. The IL-2 receptor system consists of three non-covalently linked subunits termed IL-2Ralpha, IL-2Rbeta, and IL-2Rgamma.The IL-2Ralpha is a type I transmembrane protein consisting of a 219 amino acid extracellular domain, a 19 amino acid transmembrane domain and a 13 amino acid intracellular domain, which is not involved in the transduction of IL-2 signals.Proteolytic processing of IL-2Ralpha releases the entire extracellular domain of IL-2Ralpha thereby generating a 219 amino acid soluble protein called soluble IL-2Ralpha (sIL-2Ralpha).The homodimeric form binds IL-2 (KD=10nM) and facilitates IL-2 signaling.The secreted sIL-2Ralpha is expressed on leukemia cells, lymphoma cells, newly activated T and B cells, as well as on approximately 10% of NK cells.Recombinant human sIL-2Ralpha is a 24.8kD protein containing 219 amino acid residues consisting of only the extracellular domain of IL-2Ralpha. Due to glycosylation, IL-2Ralpha has an approx |
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| Size | 5ug, 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143502 |
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| Order / More Info | sIL-2Rα, Recombinant, Human (soluble IL-2 receptor, TAC-antigen, CD25 antigen) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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