| 产品详情 |
| Edit |   |
|---|
| Product Name | Sialin, Human (Control Peptide) |
|---|
| Description | Highly purified. A 17 aa synthetic peptide witin 1st putative extracellualr domain (between 1-2 TM) of human silain was synthesized, conjugated to KLH, and antibodies generated in rabbits. Sialic acid storage disease (SASD) are autosomal recessive neurdegenerative disorders that may present as a severa infantile form (ISSD) or a slowly progressive adult form (Salla disease) prevalent in Finland. The patients exccrete large amounts of free sialic acid in urine. A H+/anionic sugar symporter mechanism for sialinc acid and glucoronic acid is impaired in lysosomal membranes from Sall and ISSD. A new gene, termed Sialin (SLC17A5; human 495 aa, chromosome 6q14-q15) belonging to the family of anion/cation symporters (ACS) has been found to be mutated in sialic acid storage disease. Sialin is predicted to contain up to 12 TM domains with N and C-termini located in the cytoplasm. Sialin has 37%, 34%, and 16% sequence identity with BNPI/VGLUT1, NPT1 (Napi-I), and E. coli hexuronate (EcHex) transp |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | S1013-31M1 |
|---|
| Price | |
|---|
| Order / More Info | Sialin, Human (Control Peptide) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|