| 产品详情 |
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| Product Name | Sialoprotein II, Bone, Recombinant, Mouse |
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| Description | Purity ~90% (SDS-PAGE, reducing conditions). IBSP (integrinbinding sialoprotein; also BSP or bone sialoprotein II) is a 5575kD, secreted, variably glycosylated, monomeric noncollagenous member of the SIBLING family of extracellular matrix (ECM) proteins. It is principally associated with the early stages of bone mineralization. Mouse BSP is synthesized as a 324aa precursor that contains a 16aa signal sequence and a 308aa mature region. The mature segment is divided into a basic Nterminus (aa17-62), a central region (aa63233), and an acidic Cterminus (aa234317). Functional segments associated with the mature molecule include a type I collagen binding domain (aa1946), two nonRGD cell binding sites (aa3057 and 261281), an RGD alpha-v-b-3 integrinbinding site (aa286288) and two regions that are potential hydroxyapatite (HAp) nucleation domains (aa7683 and 151158). HAp formation requires a BSP nucleation site composed of at least eight consecutive glutamic acid residues and, |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Sialoprotein II, Bone, Recombinant, Mouse (Bone Sialoprotein 2, Bone Sialoprotein II, BSP II, Cell-binding Sialoprotein, Integrin-binding Sialoprotein, IBSP, BNSP) |
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| Gene, Accession, CAS # | Accession: NP_032344 |
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| Catalog # | S1013-32P |
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| Order / More Info | Sialoprotein II, Bone, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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