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| Product Name | Kirrel2, Recombinant, Mouse |
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| Description | Purity ≥ 90%, as determined by SDS-PAGE under reducing conditions and visualized by silver stain.Endotoxin: ≤ 1EU/1ug. Kirrel2 (kin of irregular chiasm-1-like 2), also known as filtrin, NEPH3 (nephrin-like 3) or NLG1 (nephrin-like gene 1), is a 107kD type I transmembrane adhesion protein belonging to the immunoglobulin superfamily.1, 2 Kirrel2 is one of several proteins expressed both in pancreatic islet b cells and kidney glomerulus, and is also found in brain and lymph nodes.1-9 Mouse Kirrel2 cDNA encodes a 700 aa protein that contains a 16 aa signal sequence, a 491 aa extracellular domain with five C2-type Ig-like domains, a 21 aa transmembrane sequence and a 172 aa intracellular domain with a nephrin-like, conserved podocin binding site (mouse aa 589-598).4, 5 An extracellular RGD sequence allows for cell attachment.4 The extracellular domain of mouse Kirrel2 shares 96%, 86%, 85% and 85% amino acid (aa) identity with rat, human, equine and bovine Kirrel2, respectively. It shares 3 |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Kirrel2, Recombinant, Mouse (Kin of Irregular Chiasm-1-Like 2, Nephrin-like 3, NEPH, Nephrin-like Gene 1, NLG1) |
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| Gene, Accession, CAS # | Accession: NP_766486 |
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| Catalog # | K1870-15 |
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| Order / More Info | Kirrel2, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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