| 产品详情 |
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| Antigenic Specificity | RIP2 |
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| Clone | 28D3 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 κ |
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| Format | Protein G purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, IP |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RIP2 (28D3) Monoclonal Antibody. • Target Background: Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. Contributes to the tyrosine phosphorylation of the guanine exchange factor ARHGEF2 through Src tyrosine kinase leading to NF-kappaB activation by NOD2. Once recruited, RIPK2 autophosphorylates and undergoes 'Lys-63'-linked polyubiquitination by E3 ubi |
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| Immunogen | Recombinant human protein purified from E.coli (His-RIP2) |
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| Other Names | CCK; RICK; RIP2; CARD3; GIG30; CARDIAK; Receptor-interacting serine/threonine-protein kinase 2; CARD-containing interleukin-1 beta-converting enzyme-associated kinase; CARD-containing IL-1 beta ICE-kinase; RIP-like-interacting CLARP kinase; Receptor-interacting protein 2; RIP-2; Tyrosine-protein kinase RIPK2; RIPK2; UNQ277/PRO314/PRO34092 |
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| Gene, Accession # | Gene ID: 8767, SwissProt: O43353 |
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| Catalog # | bsm-50342M |
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| Price | |
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| Order / More Info | RIP2 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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