产品详情 |
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Antigenic Specificity | DDR2 |
Clone | 3B11E4 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:200-1:1000, Immunofluorescence: 1/200 - 1/1000, Immunohistochemistry: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DDR2 Monoclonal Antibody (3B11E4). Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel sub |
Immunogen | n/a |
Other Names | TKT; MIG20a; NTRKR3; TYRO10; DDR2 |
Gene, Accession # | Entrez: 4921; Uniprot: Q16832 |
Catalog # | MA5-15356 |
Price | |
Order / More Info | DDR2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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