| 产品详情 |
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| Product Name | Podoplanin (PDPN) protein (His tag) |
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| Description | Podoplanin is a small mucin-like type-1 transmembrane protein, typically expressed in various specialized cell types throughout the body. Podoplanin is a type-I integral membrane glycoprotein with diverse distribution in human tissues. PDPN physiological function is related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. PDPN is expressed in lymphatic progenitor cells and afterwards during mouse development in lymphatic endothelial cells. Podoplanin is a specific marker for lymph vessel endothelial cells. Over-expression of podoplanin significantly elevates endothelial cell adhesion, migration, and tube formation. Inhibition of Podoplanin expression decreases cell adhesion in human dermal lymphatic endothelial cells. Podoplanin is used as a specific marker for lymphatic endothelium in histopathology. Podoplanin expression is increased in nearly all human colon, rectum, and small intestine tumors. AGGRUS may serve as a diagnostic marker that distinguishes seminomas, the majority of which over express the protein, from embryonal carcinoma in testicular germ cell tumors Synonyms: Podoplanin, Glycoprotein 36, PA2.26 antigen, T1A, GP36, GP40, Gp38, OTS8, T1A2, HT1A-1, PA2.26, T1-alpha, PDPN |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PDPN|AGGRUS|GP36|GP40|Gp38|HT1A-1|OTS8|PA2.26|T1A|T1A-2|OTS-8|RANDAM-2|T1-alpha|T1a|T1alpha|E11|RTI40 |
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| Gene, Accession, CAS # | Gene ID: 10630 |
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| Catalog # | ABIN807357 |
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| Order / More Info | Podoplanin (PDPN) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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