产品详情 |
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Antigenic Specificity | Complement C4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Complement C4 Polyclonal Antibody. This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, |
Immunogen | n/a |
Other Names | C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2, C4A anaphylatoxin, Rodgers form of C4, acidic C4, acidic complement C4, complement C4-A |
Gene, Accession # | Entrez: 720; Uniprot: P0C0L4 |
Catalog # | PA5-29133 |
Price | |
Order / More Info | Complement C4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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