产品名称 RGDS from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H11563
产品价格 现货询价,电话:010-67529703
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产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NameRGDS
DescriptionPurity >97% by HPLC. Tetrapeptide that supports fibroblast attachment and inhibits fibronectin binding to platelets. The characteristic amino acid sequence, Arg-Gly-Asp (RGD), which was originally found within the central cell-binding domain of fibronectin, is present in a number of extracellular matrix proteins, binds some integrins such as 3-Beta1 (VLA-3), 5-Beta1 (VLA-5), v-Beta3 (GPIIb/IIIa) and vitronectin receptor (VN-R) on the cell surface, and affects tumour cell functions including adhesion, invasion and migration. Furthermore, RGD-containing peptides have been reported to inhibit tumour metastasis, tumour-induced angiogenesis and tumour-elicited platelet aggregation.
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Other Names(3S)-3-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-[[(2S)-1,3-dihydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
Gene, Accession, CAS #CAS: 91037-65-9
Catalog #LS-H11563
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Order / More InfoRGDS from LIFESPAN BIOSCIENCES INC.
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