| 产品详情 |
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| Product Name | Recombinant Human Collagen alpha-2 (IV) chain (COL4A2), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 28.3kDa. Partial: 1493-1712aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Type IV collagen is the major structural component of glomerular basent mbranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.Canstatin, a cleavage product corresponding to the collagen alpha 2 (IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial mbrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | COL4A2, UniProt: P08572 |
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| Catalog # | RPC24283 |
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| Price | |
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| Order / More Info | Recombinant Human Collagen alpha-2 (IV) chain (COL4A2), partial from BIOMATIK |
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| Product Specific References | n/a |
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