| 产品详情 |
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| Antigenic Specificity | PCGF1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PCGF1 Polyclonal Antibody. Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin- dependent kinase inhibitor, CDKN1A. Transcriptional repressor that may be targeted to the DNA by BCL6; this transcription repressor activity may be related to PKC signaling pathway. Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). Promotes cell cycle progression and enhances cell proliferation as well. May have a positive role in tumor cell growth by down- regulating CDKN1A. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a co |
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| Immunogen | n/a |
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| Other Names | Polycomb group RING finger protein 1, Nervous system Polycomb-1, NSPc1, RING finger protein 68, PCGF1, NSPC1, RNF68 |
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| Gene, Accession # | Entrez: 312480, 69837, 84759; Uniprot: Q6DLV9, Q8R023, Q9BSM1 |
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| Catalog # | PA5-49390 |
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| Price | |
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| Order / More Info | PCGF1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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