| 产品详情 |
| Edit |   |
|---|
| Product Name | Human LD78 / CCL3L1 Protein (Recombinant) |
|---|
| Description | Purity >95% by non-reducing SDS-PAGE and HPLC, MW: 7.8 kDa (SDS-PAGE). LD78-beta/CCL3L1 is a proinflammatory chemokine and the isoform of Macrophage Inflammatory Protein-1 alpha (MIP-1 alpha). LD78-beta is secreted by most mature leukocytes, predominantly macrophages, and its major receptor is the G-protein coupled receptor CCR5, which is also the co-receptor used by the HIV-1 virus for cell entry. LD78-beta has superior antiviral activity and induces a variety of immune cells, particularly CD8+ T cells and immature dendritic cells. LD78-beta attracts lymphocytes and macrophages to sites of inflammation and infection, and its functions are inhibited by Interleukin-4, Interleukin-10, and Interleukin-13. Importantly, the copy number variation of LD78-beta is associated with HIV susceptibility, indicating LD78-beta's critical role in the disease.Recombinant human LD78-beta/CCL3L1 (rhLD78-beta) produced in E.coli is a single non-glycosylated polypeptide chain containing 70 amino acids. A fully biologically active molecule, rhLD78-beta has a molecular mass of 7.8 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | CCL3L1, 464.2, C-C motif chemokine 3-like 1, D17S1718, G0S19-2, LD78, LD78BETA, SCYA3L, SCYA3L1, LD78-beta(1-70), MIP1AP, PAT 464.2 |
|---|
| Gene, Accession, CAS # | CCL3L1, Gene ID: 6349 |
|---|
| Catalog # | LS-G27261 |
|---|
| Price | |
|---|
| Order / More Info | Human LD78 / CCL3L1 Protein (Recombinant) from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|