| 产品详情 |
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| Product Name | TNP-470 |
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| Description | Purity >98%. TNP-470 is a synthetic analog of fumagillin that inhibits angiogenesis. It irreversibly inactivates methionine aminopeptidase-2 (MetAP2; IC50 = 2 µM), blocking endothelial cell proliferation in vitro and angiogenesis in vivo . It is without effect on MetAP1. TNP-470 has therapeutic potential in cancer and microsporidiosis. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester N-(2-chloroacetyl)-carbamic acid, AGM-1470, NSC 642492, O-(Chloroacetyl-carbamoyl) Fumagillol |
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| Gene, Accession, CAS # | CAS: 129298-91-5 |
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| Catalog # | LS-H10245 |
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| Order / More Info | TNP-470 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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