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| Product Name | Recombinant Rat Integrin beta-4 (Itgb4), partial |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 92.2kDa. Extracellular Domain: 28-713aa. N-terminal 6xHis-SUMO-tagged. Rattus norvegicus (Rat). Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | GP150; CD_antigen: CD104 |
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| Gene, Accession, CAS # | Itgb4, UniProt: Q64632 |
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| Catalog # | RPC20805 |
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| Order / More Info | Recombinant Rat Integrin beta-4 (Itgb4), partial from BIOMATIK |
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| Product Specific References | n/a |
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