| 产品详情 |
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| Product Name | SP-2509 |
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| Description | Purity >98% by HPLC. SP-2509 is a reversible inhibitor of Lysine-specific demethylase (LSD1) (IC50 = 13 nM). It has no effect on monoamine oxidases A and B. SP2509 attenuates the binding of LSD1 to CoREST, allowing increased methylation of H3K4 and driving increased expression of p21, p27, and CCAAT/enhancer binding protein a in cultured acute myeloid leukemia (AML) cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-(4-morpholinylsulfonyl)-benzoic acid (2E)-2-[1-(5-chloro-2-hydroxyphenyl)ethylidene]hydrazide |
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| Gene, Accession, CAS # | CAS: 1423715-09-6 |
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| Catalog # | LS-H3497 |
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| Order / More Info | SP-2509 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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