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| Product Name | GW 9508 |
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| Description | Purity >97%. GPR40 (free fatty acid receptor 1; FFAR1) and GPR120 (FFAR4) are G protein-coupled receptors (GPCR) that are activated by medium and long-chain fatty acids. In addition, there is evidence of a link between GPR40 and the ability of fatty acids to acutely potentiate insulin secretion. GW 9508 is a small-molecule agonist of GPR40 and GPR120. Stimulation of intracellular Ca2+ mobilization by GW 9508 in human embryonic kidney (HEK) 293 cells expressing GPR40 and GPR120 was observed with EC50 values of 47 nM and 2.2 µM, respectively. GW 9508 dose dependently potentiates glucose-stimulated insulin secretion and the KCl-mediated increase in insulin secretion in MIN6 cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[[(3-phenoxyphenyl)methyl]amino]-benzenepropanoic acid |
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| Gene, Accession, CAS # | CAS: 885101-89-3 |
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| Catalog # | LS-H24 |
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| Order / More Info | GW 9508 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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