| 产品详情 |
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| Product Name | GW-501516 |
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| Description | Purity >98% by NMR, TLC. GW-501516 is a potent and selective PPARd (NR1C2) agonist, EC50=1.2 nM and 1000-fold selective over other PPAR subtypes. Induces apolipoprotein A1-mediated cholesterol efflux in vitro. Improves hematopoietic stem cell maintenance. Prevents downregulation of AMPK caused by a high-fat diet in liver and increases fatty acid oxidation. Upregulates human Sirt1 via Sp1 activation. Along with exercise, GW-501516 synergistically increases running endurance. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazoyl]methyl]thio]phenoxy]acetic acid |
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| Gene, Accession, CAS # | CAS: 317318-70-0 |
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| Catalog # | LS-H14517 |
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| Order / More Info | GW-501516 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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